Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Old hearts age backwards: transplanted organs adjust to host's biological age Tracking the biological age of grafted organs suggests that donor pools could be expanded to boost organ availability. Featured Content Paid to peer review: firms are paying researchers to assess manuscripts for journals Freelance peer-review jobs through third-party companies raise practical and ethical questions. Miryam Naddaf News 28 Sep 2026 Paid to peer review: firms are paying researchers to assess manuscripts for journals Freelance peer-review jobs through third-party companies raise practical and ethical questions. Exclusive: Sham scientific societies are misleading star researchers A Nature investigation reveals a network of organizations that have been building their ranks through deceptive practices. Max Kozlov News Feature 25 Sep 2026 Exclusive: Sham scientific societies are misleading star researchers A Nature investigation reveals a network of organizations that have been building their ranks through deceptive practices. The gene-regulatory evolution of the human skeleton Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis -regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal tissue. Yizhi Yan Nadav Mishol David Gokhman Article Open Access 23 Sep 2026 The gene-regulatory evolution of the human skeleton Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis -regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal tissue. Daily briefing: Old hearts ‘de-age’ in younger people Epigenetic 'clocks' suggest that transplanted organs adjust to the host's biological age. Plus, a new biography of Stephen Hawking and how sham societies are misleading star researchers. Flora Graham Nature Briefing 28 Sep 2026 Daily briefing: Old hearts ‘de-age’ in younger people Epigenetic 'clocks' suggest that transplanted organs adjust to the host's biological age. Plus, a new biography of Stephen Hawking and how sham societies are misleading star researchers. Contents Subscribe Current Issue 24 Sep 2026 AI can widen science — but only if institutions stop rewarding the already measurable Funders, journals and universities must reward the creation of new scientific terrain, not just the efficient mining of old ground. Guowei Huang Xiang Hu Zhicheng Lin Comment 29 Sep 2026 AI can widen science — but only if institutions stop rewarding the already measurable Funders, journals and universities must reward the creation of new scientific terrain, not just the efficient mining of old ground. AI-powered medical devices must be tested in real-world settings Editorial 29 Sep 2026 AI-powered medical devices must be tested in real-world settings How to put people first in cyberspace Chris Stokel-Walker Book Review 29 Sep 2026 How to put people first in cyberspace Chris Stokel-Walker Chinese-owned science journal created to rival the best Xiaoying You News 29 Sep 2026 Chinese-owned science journal created to rival the best Vaping in childhood has bigger health risks than we’d thought William D. Carroll Francis J. Gilchrist Comment 28 Sep 2026 Vaping in childhood has bigger health risks than we’d thought William D. Carroll Francis J. Gilchrist Stephen Hawking biography explores an ‘exceptionally clear, uncluttered mind’ Neil Turok Book Review 28 Sep 2026 Stephen Hawking biography explores an ‘exceptionally clear, uncluttered mind’ China now leads the world in trials for next-gen CAR-T therapies Rachel Fieldhouse News 28 Sep 2026 China now leads the world in trials for next-gen CAR-T therapies Rachel Fieldhouse Latest Reviews & Analysis Strange and beautiful creatures spotted on the Challenger expedition A genus of soil-dwelling beetle discovered in Italy, and a glimpse at the wonders of the deep sea, in our weekly dip into Nature ’s archive. News & Views 29 Sep 2026 The cost of lost labour on a warming planet Researchers quantify the economic damage caused by climate-change-related heat stress on the global workforce. Holly Smith News & Views 29 Sep 2026 A new chapter in targeting kinase enzymes in cancer Inhibitors of tyrosine kinase enzymes have been a cornerstone in precision cancer treatments. Now, targeted protein degraders could reshape therapeutic options. Alice T. Shaw News & Views 29 Sep 2026 Brain lipids are organized into zones — and reorganized during pregnancy A map of fats across the whole mouse brain reveals a spatial architecture that differs from that seen in gene-expression and protein atlases. Evan Macosko News & Views 23 Sep 2026 Efficient yet stable large perovskite solar modules made using surface treatment Non-uniformities in the layer of passivator molecules, which are used to fix defects and protect the surface of perovskite material in solar cells, can limit the durability of the resulting modules. Large modules treated instead with chemically stable lead carboxylate passivators were efficient, reliable and had a higher yield than did commercial silicon modules. Research Briefing 23 Sep 2026 Strange and beautiful creatures spotted on the Challenger expedition A genus of soil-dwelling beetle discovered in Italy, and a glimpse at the wonders of the deep sea, in our weekly dip into Nature ’s archive. News & Views 29 Sep 2026 Strange and beautiful creatures spotted on the Challenger expedition A genus of soil-dwelling beetle discovered in Italy, and a glimpse at the wonders of the deep sea, in our weekly dip into Nature ’s archive. The cost of lost labour on a warming planet Researchers quantify the economic damage caused by climate-change-related heat stress on the global workforce. Holly Smith News & Views 29 Sep 2026 The cost of lost labour on a warming planet Researchers quantify the economic damage caused by climate-change-related heat stress on the global workforce. A new chapter in targeting kinase enzymes in cancer Inhibitors of tyrosine kinase enzymes have been a cornerstone in precision cancer treatments. Now, targeted protein degraders could reshape therapeutic options. Alice T. Shaw News & Views 29 Sep 2026 A new chapter in targeting kinase enzymes in cancer Inhibitors of tyrosine kinase enzymes have been a cornerstone in precision cancer treatments. Now, targeted protein degraders could reshape therapeutic options. Brain lipids are organized into zones — and reorganized during pregnancy A map of fats across the whole mouse brain reveals a spatial architecture that differs from that seen in gene-expression and protein atlases. Evan Macosko News & Views 23 Sep 2026 Brain lipids are organized into zones — and reorganized during pregnancy A map of fats across the whole mouse brain reveals a spatial architecture that differs from that seen in gene-expression and protein atlases. Efficient yet stable large perovskite solar modules made using surface treatment Non-uniformities in the layer of passivator molecules, which are used to fix defects and protect the surface of perovskite material in solar cells, can limit the durability of the resulting modules. Large modules treated instead with chemically stable lead carboxylate passivators were efficient, reliable and had a higher yield than did commercial silicon modules. Research Briefing 23 Sep 2026 Efficient yet stable large perovskite solar modules made using surface treatment Non-uniformities in the layer of passivator molecules, which are used to fix defects and protect the surface of perovskite material in solar cells, can limit the durability of the resulting modules. Large modules treated instead with chemically stable lead carboxylate passivators were efficient, reliable and had a higher yield than did commercial silicon modules. A plant that reproduces sexually but has clone-like offspring Research Briefing 23 Sep 2026 Vast cellular gene-expression atlas could transform how scientists understand brain ageing and disease Jennifer E. Below News & Views 23 Sep 2026 The human skeleton’s unique adaptations relied on gene regulatory changes Audrey M. Arner Amanda J. Lea News & Views 23 Sep 2026 Gravitational forces inside Earth drag some decades out — and make others fly by Dominique Jault Paolo Personnettaz News & Views 23 Sep 2026 A plant that reproduces sexually but has clone-like offspring Research Briefing 23 Sep 2026 A plant that reproduces sexually but has clone-like offspring Vast cellular gene-expression atlas could transform how scientists understand brain ageing and disease Jennifer E. Below News & Views 23 Sep 2026 Vast cellular gene-expression atlas could transform how scientists understand brain ageing and disease Jennifer E. Below The human skeleton’s unique adaptations relied on gene regulatory changes Audrey M. Arner Amanda J. Lea News & Views 23 Sep 2026 The human skeleton’s unique adaptations relied on gene regulatory changes Audrey M. Arner

Gravitational forces inside Earth drag some decades out — and make others fly by Dominique Jault Paolo Personnettaz News & Views 23 Sep 2026 Gravitational forces inside Earth drag some decades out — and make others fly by Dominique Jault Paolo Personnettaz Latest Research articles Chiral oxazolidinones via biocatalytic aziridination of unactivated alkenes Zi-Qi Li Deirdre Hanley Frances H. Arnold Article 23 Sep 2026 Chiral oxazolidinones via biocatalytic aziridination of unactivated alkenes Frances H. Arnold The gene-regulatory evolution of the human skeleton Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis -regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal tissue. Yizhi Yan Nadav Mishol David Gokhman Article Open Access 23 Sep 2026 The gene-regulatory evolution of the human skeleton Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis -regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal tissue. The anthropogenic fingerprint on emerging infectious diseases Emerging infectious disease outbreak risks are ubiquitous worldwide, and highest in landscapes where people, livestock and fragmented natural ecosystems coexist, but detection and data on outbreaks are currently limited by inequalities in healthcare access. Rory Gibb Sadie J. Ryan Colin J. Carlson Article Open Access 23 Sep 2026 The anthropogenic fingerprint on emerging infectious diseases Emerging infectious disease outbreak risks are ubiquitous worldwide, and highest in landscapes where people, livestock and fragmented natural ecosystems coexist, but detection and data on outbreaks are currently limited by inequalities in healthcare access. Colin J. Carlson Gravitational torque drives multidecadal variations in length of day Multidecadal fluctuations in Earth’s length of day are shown to be driven by gravitational torque and resisted by electromagnetic and topographic forces, improving our understanding of the material properties and dynamics of Earth’s deep interior. Huifeng Zhang Mathieu Dumberry Article Open Access 23 Sep 2026 Gravitational torque drives multidecadal variations in length of day Multidecadal fluctuations in Earth’s length of day are shown to be driven by gravitational torque and resisted by electromagnetic and topographic forces, improving our understanding of the material properties and dynamics of Earth’s deep interior. Mathieu Dumberry Single-nucleus transcriptome-wide association study of human brain disorders Single-nucleus transcriptomics across diverse populations is used to explore how genetic risk for brain disorders affects specific cell types, revealing previously hidden gene–trait associations and conserved, cell-type-specific mechanisms. Sanan Venkatesh Roman Kosoy Panos Roussos Article Open Access 23 Sep 2026 Single-nucleus transcriptome-wide association study of human brain disorders Single-nucleus transcriptomics across diverse populations is used to explore how genetic risk for brain disorders affects specific cell types, revealing previously hidden gene–trait associations and conserved, cell-type-specific mechanisms. Sanan Venkatesh Trending - Altmetric Reference genomes and fossils revise bat family phylogeny and biogeography Reference genomes and fossils revise bat family phylogeny and biogeography The worst El Niño in recorded history is brewing — here’s how governments must prepare The worst El Niño in recorded history is brewing — here’s how governments must prepare Exclusive: Sham scientific societies are misleading star researchers Exclusive: Sham scientific societies are misleading star researchers The anthropogenic fingerprint on emerging infectious diseases The anthropogenic fingerprint on emerging infectious diseases Multiple Positions Open in the Stomatology Hospital, ZJUSS Leaders or Principal Investigators, Faculty and Postdoc positions are open all year Hangzhou, Zhejiang (CN) The Stomatology Hospital, Zhejiang University School of Medicine Multiple Positions Open in the Stomatology Hospital, ZJUSS Leaders or Principal Investigators, Faculty and Postdoc positions are open all year Hangzhou, Zhejiang (CN) The Stomatology Hospital, Zhejiang University School of Medicine Postdoctoral Fellows Recruitment Announcement at Shenzhen Bay Laboratory Substantial Funding for Postdoctoral Research Shenzhen, Guangdong (CN) Shenzhen Bay Laboratory Postdoctoral Fellows Recruitment Announcement at Shenzhen Bay Laboratory Substantial Funding for Postdoctoral Research Shenzhen, Guangdong (CN) Shenzhen Bay Laboratory Faculty Positions at SUSTech Department of Biomedical Engineering We seek outstanding applicants for full-time tenure-track/tenured faculty positions. Positions are available for both junior and senior-level. Shenzhen, Guangdong, China Southern University of Science and Technology (Biomedical Engineering) Faculty Positions at SUSTech Department of Biomedical Engineering We seek outstanding applicants for full-time tenure-track/tenured faculty positions. Positions are available for both junior and senior-level. Shenzhen, Guangdong, China Southern University of Science and Technology (Biomedical Engineering) Postdoc Opportunity at MSK: Research Scholar, Computational Oncology/Immuno Oncology We are seeking a highly motivated computational biology postdoctoral fellow New York City, New York (US) Memorial Sloan Kettering Cancer Center Postdoc Opportunity at MSK: Research Scholar, Computational Oncology/Immuno Oncology We are seeking a highly motivated computational biology postdoctoral fellow New York City, New York (US) Memorial Sloan Kettering Cancer Center Postdoctoral Fellow, Computational Immuno-Oncology and Immune-Related Adverse Events Join the Reznik Laboratory within MSK’s Computational Oncology Service New York City, New York (US) Memorial Sloan Kettering Cancer Center Postdoctoral Fellow, Computational Immuno-Oncology and Immune-Related Adverse Events Join the Reznik Laboratory within MSK’s Computational Oncology Service New York City, New York (US) Memorial Sloan Kettering Cancer Center Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily. 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