The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Last update: January 14, 2025 PubMed contains citations and abstracts of biomedical literature from several NLM literature resources, including MEDLINE—the largest component of the PubMed database. PubMed data are available via our FTP servers and via the E-utilities API. On this page, learn how to access, use, and stay informed about PubMed data. What is the PubMed annual baseline ? What are the PubMed daily update files ? How can I find out when the PubMed annual baseline is released ? Are there any restrictions on use of PubMed data? Is there an API for PubMed data ? Where can I learn about data elements in the PubMed XML? Subscribe for updates Please subscribe to our listserv to receive notifications and significant updates such as the annual baseline release at the end of each year. Get PubMed data via FTP Note: Binary mode must be used when downloading data from our FTP servers. Annual baseline Once a year, NLM produces a baseline set of PubMed citation records in XML format for download; the baseline file is a complete snapshot of PubMed data. When using this data in a local database, the best practice is to overwrite your local data each year with the baseline data. Daily update files Each day, NLM produces update files that include new, revised, and deleted citations. If you are incorporating these update XML files into a local database, load the baseline files first, then load the daily update files in numerical order. Revised or deleted citations should replace existing citations in your local database. More than one update file may become available on the same day. Get PubMed data via API

Insider's guide to E-utilities These educational resources help users explore powerful and flexible ways of accessing NLM data, with a focus on accessing PubMed data via the E-utilities API. E-utilities help The Entrez Programming Utilities (E-utilities) consist of eight server-side programs that provide a stable interface into the Entrez query and database system at NCBI. The E-utilities help includes: E-utilities Quick Start E-utilities In-Depth E-utilities Usage Guidelines and Requirements Use PubMed data Terms and conditions Please see the Terms and Conditions in the README.txt included with the baseline and update files. Downloading data from our FTP servers indicates your acceptance of these Terms and Conditions. DTD Documentation PubMed data conform to the current PubMed DTD . The DTD documentation provides annotations and examples for all elements and attributes defined in the PubMed DTD. Additional resources PubMed Data Field Descriptions Download MeSH data List of All Journals Cited in PubMed NCBI Literature Resources MeSH PMC Bookshelf Disclaimer The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.