Primary Antibodies › NeuN Antibodies {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}} {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}} Cite NeuN Monoclonal Antibody (1B7) NeuN Antibody (MA5-33103) in ICC/IF {{$ctrl.videoDesc}} {{$ctrl.videoLongDesc}} Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation. 免疫组化（石蜡） (IHC (P)) 免疫组化（冰冻） (IHC (F))

免疫细胞化学 (ICC/IF) Fox-3, also known as NEUN, HRNBP3, RBFOX3 (RNA binding protein, fox-1) or Fox-1 homolog C, is a 350 amino acid protein that contains one RRM (RNA recognition motif) domain. Localized to both the nucleus and cytoplasm, Fox-3 is suggested to regulate alternative splicing events. Fox-3 is encoded by a gene located on human chromosome 17, which is comprised over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and LiFraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. 仅用于科研。不用于诊断过程。未经明确授权不得转售。 蛋白别名: FLJ56884; FLJ58356; fox 1 homolog (C. elegans) 3; fox-1 homolog C; fox1 homolog C; FOX3NeuN; hexaribonucleotide binding protein 3; hexaribonucleotide binding protein 3 (HRNBP3); neuN antigen; neuronal nuclear antigen A60; neuronal nuclei; neuronal nuclei antigen; RFOX3; RNA binding protein; RNA binding protein, fox-1 homolog 3; RNA-binding protein; unnamed protein product 基因别名: FOX-3; FOX3; HRNBP3; NEUN; Neuna60; RGD1560070 UniProt ID: (Bovine) Q0VD23 , (Human) A6NFN3 , (Mouse) Q8BIF2 Entrez Gene ID: (Bovine) 511773 , (Human) 146713 , (Mouse) 52897 , (Rat) 287847 Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented. 只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。* 获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。 Your item s have has been added!